Description
Meftal 500 Tablet (Mefenamic Acid 500mg)
Meftal 500 Tablet (Mefenamic Acid 500mg) is an effective non-steroidal anti-inflammatory drug (NSAID) widely used to manage moderate to severe pain. It is commonly prescribed for conditions such as menstrual pain, headaches, muscle aches, joint pain, and dental pain. Its efficacy lies in alleviating pain and reducing inflammation by blocking the release of certain chemical messengers. The tablet should be taken with food to minimize stomach discomfort, and its dosage and duration will be tailored to your specific needs by your healthcare provider.
Uses of Meftal 500 Tablet (Mefenamic Acid 500mg)
- Treatment of menstrual pain
- Treatment of headaches
- Treatment of muscle pain
- Treatment of joint pain
- Treatment of dental pain
- Treatment of menstrual pain: Meftal 500 Tablet (Mefenamic Acid 500mg) is particularly effective for alleviating menstrual cramps and pain associated with menstruation, providing relief by reducing inflammation.
- Treatment of headaches: This medication helps in managing headaches, including migraines, by blocking the brain’s chemical messengers that signal pain.
- Treatment of muscle pain: It delivers relief from muscle discomfort and inflammation which can arise from overexertion, injury, or other conditions.
- Treatment of joint pain: Meftal 500 Tablet (Mefenamic Acid 500mg) is also effective in reducing joint pain and inflammation, commonly seen in arthritis.
- Treatment of dental pain: This tablet is highly effective in managing dental pain, including pain that originates from dental procedures or toothaches.
Safety & Precautions
- Inform your doctor if you have asthma.
- Notify your doctor of any history of stomach ulcers.
- Report any existing heart diseases to your doctor.
- Discuss any history of high blood pressure.
- Inform your doctor if you have liver disease.
- Notify your doctor if you are pregnant or breastfeeding.
- Discuss any kidney issues you might have.
- Avoid alcohol while taking this medication.
- Do not drive if you experience dizziness or decreased alertness.
- Continue medication as prescribed to avoid incomplete treatment.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.
- Vomiting
- Stomach pain
- Nausea
- Headache
- Dizziness
- Diarrhea
- Indigestion
- High blood pressure
- Rash
- Itching
- Shortness of breath
- Swelling of face or lips
- Stomach ulcers
- Liver dysfunction
- Kidney issues
FAQ
1. Can I take Meftal 500 Tablet (Mefenamic Acid 500mg) during pregnancy?
Meftal 500 Tablet (Mefenamic Acid 500mg) may not be safe to use during pregnancy. Limited studies in humans suggest harmful effects on the developing baby, while animal studies have shown risks. It is crucial to discuss with your doctor, who can weigh the benefits and any potential risks before prescribing it.
2. Is Meftal 500 Tablet (Mefenamic Acid 500mg) safe during breastfeeding?
Meftal 500 Tablet (Mefenamic Acid 500mg) is generally considered safe during breastfeeding. Human studies indicate that the drug does not pass into breastmilk in significant amounts and is not harmful to the baby. However, it is always best to consult your doctor before use.
3. Can I drive after taking Meftal 500 Tablet (Mefenamic Acid 500mg)?
Meftal 500 Tablet (Mefenamic Acid 500mg) may decrease alertness, affect your vision, or make you feel sleepy and dizzy. It is advisable not to drive or operate heavy machinery if these symptoms occur. Ensure you understand how the medication affects you before engaging in such activities.
4. Can I consume alcohol while taking Meftal 500 Tablet (Mefenamic Acid 500mg)?
It is unsafe to consume alcohol while taking Meftal 500 Tablet (Mefenamic Acid 500mg). Alcohol can increase the risk of stomach bleeding and other gastrointestinal issues. To avoid adverse interactions, it is best to refrain from alcohol consumption during your treatment.
5. What should I do if I experience severe side effects from Meftal 500 Tablet (Mefenamic Acid 500mg)?
If you experience severe or persistent side effects from Meftal 500 Tablet (Mefenamic Acid 500mg), it is important to contact your doctor immediately. They may suggest ways to mitigate these symptoms or may adjust your medication to better suit your needs.
6. How should I store Meftal 500 Tablet (Mefenamic Acid 500mg)?
Store Meftal 500 Tablet (Mefenamic Acid 500mg) below 30°C in its original packaging to protect it from moisture and heat. Keep it out of reach of children and pets to avoid accidental ingestion. Always check the expiration date before use and dispose of expired medications properly.
Additional Information
Meftal 500 Tablet (Mefenamic Acid 500mg) Tablet Uses
Meftal 500 Tablet (Mefenamic Acid 500mg) tablets are multifaceted in their utility and are prescribed for various conditions involving mild and moderate visceral pain. The combination of Mefenamic Acid and Dicyclomine Hydrochloride provides a potent therapeutic effect. Below are some of the primary conditions for which Meftal 500 Tablet (Mefenamic Acid 500mg) is commonly prescribed:
- Mild to moderate visceral pains
- Inflammatory conditions with associated pain and fevers
- Dysmenorrhea (painful menstrual periods) manifested in heavy bleeding and menstrual cramps
- Colic and flank pains, especially those due to kidney stones
Meftal 500 Tablet (Mefenamic Acid 500mg) Mechanism of Action
The therapeutic efficacy of Meftal 500 Tablet (Mefenamic Acid 500mg) can be attributed to its dual-action formula involving Mefenamic Acid and Dicyclomine Hydrochloride:
- Mefenamic Acid: This NSAID works by inhibiting the prostaglandin synthetase inhibitors (PGSIs), such as COX-1 and COX-2 receptors, thereby reducing the production of prostaglandins. Prostaglandins are responsible for causing pain, inflammation, and fever. By inhibiting their synthesis, mefenamic acid effectively alleviates these symptoms.
- Dicyclomine Hydrochloride: An anticholinergic that targets muscarinic receptors in the smooth muscle lining of the stomach, intestines, and bladder, thereby reducing muscle spasms and cramping.
Meftal 500 Tablet (Mefenamic Acid 500mg) Dosage
Below is a table outlining the standard dosage guidelines for different patient categories:
| Category | Initial Dose | Subsequent Dose | Maximum Duration |
|---|---|---|---|
| Adults | 500 mg once | 250 mg every 6-8 hours | 1 week |
| Dysmenorrhea | 500 mg once | 250 mg every 6-8 hours | 3 days |
| Children (≥ 14 years) | 500 mg once | 250 mg every 6 hours | 7 days |
| Geriatric Patients | 500 mg once | 250 mg every 6-8 hours | As prescribed by doctor |
Meftal 500 Tablet (Mefenamic Acid 500mg) for COVID-19
In recent studies, Meftal 500 Tablet (Mefenamic Acid 500mg) has shown potential as a supportive treatment for COVID-19. When combined with the antiviral agent Ribavirin, Meftal 500 Tablet (Mefenamic Acid 500mg) exhibits a synergistic effect, enhancing antiviral activity. Below are key findings:
- 90% inhibitory effect against RNA viruses at a 30µM concentration
- Enhanced antiviral effects when used as combinatorial therapy
Meftal 500 Tablet (Mefenamic Acid 500mg) Indications
Meftal 500 Tablet (Mefenamic Acid 500mg) is indicated for numerous conditions involving mild and moderate visceral pain, as well as specific inflammatory disorders. The primary indications are summarized below:
- Mild and moderate abdominal pain
- Primary dysmenorrhea
- Menorrhagia (abnormally heavy menstrual bleeding and menstrual cramps)
- Febrile conditions
- Colic or flank pain
Drug Interactions of Meftal 500 Tablet (Mefenamic Acid 500mg)
It is crucial to be aware of potential drug interactions when taking Meftal 500 Tablet (Mefenamic Acid 500mg). Various combinations can lead to undesired reactions as outlined in the table below:
| Drug | Interaction Effect |
|---|---|
| Ibuprofen | Increased risk of bleeding and ulcer formation |
| Anti-coagulants/Blood Thinners | Prolongation of bleeding time |
| Other NSAIDs | Ulcer formation in the stomach |
| ACE Inhibitors | Alteration in blood pressure response |
Effect of Meftal 500 Tablet (Mefenamic Acid 500mg) in Pregnancy, Breastfeeding, and Fertility
It is vital to consider the effects of Meftal 500 Tablet (Mefenamic Acid 500mg) during pregnancy, breastfeeding, and in terms of fertility:
- Pregnancy: Can cause a decrease or disruption of blood supply from mother to fetus due to premature closure of the ductus arteriosus.
- Breastfeeding: Traces of mefenamic acid can be transported to the baby through breast milk and may cause serious side effects. Consult a doctor to weigh benefits against potential risks.
- Effects on Fertility: May prevent the rupturing of ovarian follicles, responsible for fertilization, potentially causing infertility. Discontinuation of the drug is advised for those planning to conceive.
Additional FAQs
Below is a compiled list of frequently asked questions revolving around the use of Meftal 500 Tablet (Mefenamic Acid 500mg) tablets:
- Is it safe to take Meftal 500 Tablet (Mefenamic Acid 500mg) during periods?
- Yes, Meftal 500 Tablet (Mefenamic Acid 500mg) is considered safe to use for relieving menstrual cramps, abdominal pain, and period pain.
- How long does it take for Meftal 500 Tablet (Mefenamic Acid 500mg) to work?
- After ingestion, Meftal 500 Tablet (Mefenamic Acid 500mg) takes about 2 to 3 hours for absorption. The peak effect is observed within 90 minutes, and the maximum duration of action is around 4 hours.
- Can I take 2 Meftal 500 Tablet (Mefenamic Acid 500mg) in a day?
- Yes, 2 Meftal 500 Tablet (Mefenamic Acid 500mg) can be taken in a day based on symptoms and under medical supervision.
- How many Meftal 500 Tablet (Mefenamic Acid 500mg) can be taken in a day?
- A maximum of 3 Meftal 500 Tablet (Mefenamic Acid 500mg) tablets can be taken in a day, 6 to 8 hours apart, as advised by a primary care physician.
- Can Meftal 500 Tablet (Mefenamic Acid 500mg) be taken for a headache?
- No, Meftal 500 Tablet (Mefenamic Acid 500mg) is not recommended for headaches. It is primarily used for mild to moderate visceral pain such as menstrual and abdominal cramps.
- Is Meftal 500 Tablet (Mefenamic Acid 500mg) used for loose motion?
- No, Meftal 500 Tablet (Mefenamic Acid 500mg) is not indicated for loose motion but can help relieve stomach and abdominal pain, colic, or flank pain due to kidney stones.
- Can Meftal 500 Tablet (Mefenamic Acid 500mg) be taken for stomach pain?
- Yes, Meftal 500 Tablet (Mefenamic Acid 500mg) can be taken for stomach pain. The combination of mefenamic acid and dicyclomine hydrochloride helps alleviate visceral pain and inflammation, as well as relax the musculature of the stomach and intestine.
- Can Meftal 500 Tablet (Mefenamic Acid 500mg) be taken for a toothache?
- Yes, it is effective for dental pain relief. A 1992 study demonstrated that mefenamic acid provides greater duration and intensity of pain relief compared to a combination of ibuprofen, paracetamol, and codeine.
In conclusion, Meftal 500 Tablet (Mefenamic Acid 500mg) presents itself as an effective treatment for mild to moderate visceral pain and related conditions, owing to its unique mechanism of action and broad-spectrum utility. However, it is crucial to consult healthcare professionals to tailor its use for individual needs, particularly in complex scenarios involving potential drug interactions, pregnancy, and long-term use.
Citations:
- Blue Cross Laboratories Private Ltd. Product Information.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 4032, Mefenamic acid.
- Studies on NSAIDs and COVID-19, Journal of Medical Virology, 2022.
